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Two good papers in the last few weeks, both in Vaccine.

1. Barnett et al (2004) 22: 1221-1232 Evidence that high potency foot-and-mouth disease vaccine inhibits local virus replication and prevents the 'carrier' state in sheep.

2. Eble et al (2004) 22: 1372-1378 Vaccination of pigs two weeks before infection significantly reduces transmission of foot- and-mouth disease virus. So, in summary - given an interval of 14 days following vaccination - complete protection in sheep and no virus transmission in pigs. Seems very straight forward!