American Journal of
RESEARCH Am.J.Vet.Res (Vol 64, No 7, p 805):
Benefit-cost analysis of vaccination and preemptive slaughter as a means
of eradicating foot-and-mouth disease
Thomas W. Bates, PhD; Tim E.
Carpenter, PhD; Mark C. Thurmond, DVM, PhD
ObjectiveTo assess relative costs and
benefits of vaccination and preemptive herd slaughter to control transmission of
foot-and-mouth disease (FMD) virus (FMDV).
herds and 5 sale yards located in Fresno, Kings, and Tulare counties of
ProcedureDirect costs associated with indemnity,
slaughter, cleaning and disinfecting livestock premises, and vaccination were
compared for various eradication strategies. Additional cost, total program
cost, net benefit, and benefit-cost value (B/C) for each supplemental strategy
were estimated, based in part on results of published model simulations for FMD.
Sensitivity analyses were conducted.
ResultsMean herd indemnity
payments were estimated to be $2.6 million and $110,359 for dairy and nondairy
herds, respectively. Cost to clean and disinfect livestock premises ranged from
$18,062 to $60,205. Mean vaccination cost was $2,960/herd. Total eradication
cost ranged from $61 million to $551 million. All supplemental strategies
involving use of vaccination were economically efficient (B/C range, 5.0 to
10.1) and feasible, whereas supplemental strategies involving use of slaughter
programs were not economically efficient (B-C, 0.05 to 0.8) or
Conclusions and Clinical RelevanceVaccination with a
highly efficacious vaccine may be a cost-effective strategy for control of FMD
if vaccinated animals are not subsequently slaughtered and there is no future
adverse economic impact, such as trade restrictions. Although less preferable
than the baseline eradication program, selective slaughter of highest-risk herds
was preferable to other preemptive slaughter strategies. However, indirect costs
can be expected to contribute substantially more than direct costs to the total
cost of eradication programs. (Am J Vet Res 2003;64:805812)
Received October 16, 2002.
Accepted March 12, 2003.
Department of Medicine and Epidemiology, School of Veterinary Medicine,
University of California, Davis, CA 95616. Dr. Bates present address is L-174,
Lawrence Livermore National Laboratory, Livermore, CA 94551.
part by USDA Animal Health Formula Funds, the USDA National Research Initiative
Competitive Grants Program (grant No. 35204-10173), the California Department of
Food and Agriculture, and the USDA: Animal Plant Health Inspection Service: