I wonder if our special relationship with the United States of America extends to the transfer of information about scrapie ?
 
The reason I ask is that I wonder if Dr Bill McKelvey knew about the American results, and what portion of the #94,000 was spent in air travel/accommodation across the pond ?    There seems a terrible lag (3.5 years) in getting the USA results to reach our Consumers Association..............or was that deliberate ?
 
Best wishes,
 
Bryn
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Datum:  SE 1814. 
Research Centre - Edinburgh
Principal : Dr W. McKelvey
"To determine if SCRAPIE can be transmitted by transfer of embryos from ewes INFECTED with scrapie to uninfected ewes".
Start : 1 Oct 95
Finish : 1 Sep 98
Cost: #94,000
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Ref Source : Consumers Association "Monthly Report" - May 2002.

Scrapie-resistant sheep breeds show reduced placental transmission

Scrapie in sheep can be transmitted through exposure to infected uterine and placental tissues. Susceptibility to scrapie is primarily controlled by polymorphisms in the prion protein (PrP) gene: susceptibility occurs in many breeds in sheep that are homozygous for glutamine at codon 171 of the scrapie gene, but scrapie is uncommon in sheep that are homozygous for arginine at that point, or are heterozygous arginine-glutamine.

Researchers in the USA have shown that scrapie prions accumulate in the placenta of infected pregnant ewes only if the foetuses are of the susceptible glutamine-glutamine type and not if they are the heterozygous type. Scrapie prions were not present in the uterus of non-pregnant infected ewes. The researchers suggest that the results indicate that accumulation of scrapie prions is eliminated or reduced to undetectable levels in reproductive and placental tissues if infected ewes are not pregnant or carry a foetus with a resistant genotype.

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Scrapie

Ref Site : www.defra.gov.uk/animalh/bse/bse-science/level-4-scrapie.html

Incidence of Scrapie.

Data on scrapie in sheep and goats have been collected since the disease became notifiable 1993.

Not all cases were confirmed until compulsory slaughter legislation was introduced in 1998. Interpretation of trends may therefore be unreliable.

Scrapie cases (Great Britain)

latest figures, 31 Marchl 2002

 

confirmed

pending or inconclusive

1993

328

3

1994

235

2

1995

254

1

1996

460

3

1997

508

4

1998

499

1

1999

597

2

2000

568

0

2001

294

8

2002 to 31 March

53

78